Patients who are sensitive to aspirin, ibuprofen, other nonsteroidal anti-inflammatory drugs (NSAIDs) or hypersensitivity reactions related to previous NSAID therapy. Patients in whom aspirin and other NSAIDs induce the symptom of asthma, rhinitis and urticaria. Patients with active or history of peptic ulceration, recurrent peptic ulcer/haemorrhage, varicella infection. History of gastrointestinal bleeding or perforation. Severe heart failure, renal failure or hepatic failure. Last trimester of pregnancy.
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